Sorafenib Tosylate is manufactured by Bayer and is used to treat cancer. ## Compulsory licenses Compulsory licenses have been issued for Sorafenib Tosylate in the following instance: ### India issued on March 01, 2012 [[India]]'s provisions on compulsory licences can be in the Patents Act, 1970. A compulsory licence may be granted under the following grounds: - Non-working / unmet public requirements – After 3 years from grant, a compulsory licence may be sought where the reasonable requirements of the public with respect to the patented invention have not been satisfied, or the invention is not worked in India. - Refusal to grant licence on reasonable terms / failure to supply – Where the patent owner refuses to grant licences on reasonable commercial terms and conditions (or the patent is worked but not supplied to the public on reasonable terms). - Dependent (later) patent – If a later invention cannot be worked without infringing an earlier patent, and the later invention represents a substantial technical advance of considerable economic significance, a licence may be granted to the owner of the later patent to the extent necessary. - Public interest / national emergency / anti-competitive practice / government use – The law and related provisions allow compulsory licences or government use directions in cases of public health, national emergency or anti-competitive behaviour. Procedures differ (and some requirements may be waived in emergencies). - Export to countries lacking manufacturing capacity (Section 92A) – Section 92A provides for compulsory licences for the manufacture and export of patented pharmaceutical products to countries that lack sufficient manufacturing capacity, subject to conditions and exceptions (TRIPS-consistent export mechanism). More information can be found [here](https://ipindia.gov.in/writereaddata/Portal/IPOAct/1_113_1_The_Patents_Act__1970___incorporating_all_amendments_till_1-08-2024.pdf). ## Other products issued by the same manufacturer [[Ciprofloxacine]] [[Sorafenib Tosylate]] ## Other products for the same disease [[Erlotinib]] [[Imatinib]] [[Letrozole]] [[Sunitinib, erlotinib]] [[Gemcitabine]] [[Trastuzumab-Emtansine]] [[Pertuzumab]] [[Dasatinib]] [[Docetaxel]] [[Sunitinib]]